Also worth checking out the ten entries in the competition as it gives you an idea of the standard and I don't think it'd be impossible to come up with something at least as good as those. I especially didn't think much of the current leading entry which has nice art* but the story is exposition heavy, rather clunky and just ends on the eighth page and would have benefited from someone else looking over the script (unless in the future everyone says "drat"). Better were Octane Jungle, Physikon and A Stinking Corpse** - art that complimented the story and a story arc that ended on the last page giving us enough to be interested in to check it out if it continues, which confirms my gut feeling. If I had to vote for one it'd be Octane Jungle as it seemed to work the best (the colouring and sound effects especially stood out) despite the delivery boy in a dystopia has been done before.
Also don't overlook lettering - Cards Kill was really let down by theirs.
The key is clearly promotion - it won't help an awful comic win but it could make a difference - the leading entires have less than 4,000 views so getting enough coverage to interest a few hundred people could be what nudges you into the lead.
*And I suspect it is artists you are always going to do well out of this
** I got a Lee Carter vibe from the art there