Helpful recaps'r'us:
Sinister and Dexter are 'gunsharks', contract killers working in the vast urban sprawl of Downlode, extending across most of central Europe.
They used to work for sexy crimeboss Demi Octavo, who killed her rival kingpin and husband Holy Moses Tannenbaum, before being killed herself, an event that badly shook the boys' partnership and the balance of criminal power in the city.
Out of the resulting mess, a secret clone of Moses Tannenbaum known as Apellido becomes chief crimelord of Downlode.
The boys have a range of uneasy allies, including Demi's kid sister Billi, ex-cop cyborg bar-owner Rocky Rhodes, Finny's estranged wife the crimeboss of high-tech Asian city Mangapore, and former gunshark protege Kal Cutter.
Following a complex series of cock-ups and betrayals, the lads ended up on the wrong side of both Apellido and the law. Dexter was shot and paralysed by his cop-girlfriend Tracy Weld, and Billi was badly injured. Sinister, thinking Dexter dead, fled off-planet to no-account colony Generica and assumed a new identity as 'Malone', while Kal Kutter started working for new player in town, The Mover.
The Mover turns out to be another version of Moses Tannenbaum from a parallel dimension where Downlode is rapidly losing a war of invasion, and he has decided to move his crime empire to 'our' Downlode by replacing key figures with dupes from his own parallel. These are frequently gunsharks and ne'er-do-wells who Sinister Dexter have offed in 'our' dimension, but who instead lived on because the lads themselves were killed at an early age in The Mover's world. In response, Apellido acquires some genetically engineered super-enforcers of his own, but still seems the weaker party in the War of the Moses.
Learning that Dexter is still alive, Finny comes back from Generica to break him out of prison in inventive fashion, and get him fixed up. The lads resume their partnership, but find themselves running up against foes they had thought long dead, while caught between old enemy Apellido and new power The Mover. Meanwhile Tracy Weld has been suspended and harrassed by the Downlode authorities becasue of her association with Dexter, and finally snaps and kills her 'handler'. Kal Kutter's wife is killed when the lads rescue her from The Mover, who was holding her as leverage against him. Wannabe singer Missy Solemnis, Finny's friend when he was 'Malone', has come to Downlode chasing stardom, but falls into the seedier end of The Mover's empire and is recused by Finny.
Now, The Mover sends the Demi Octavo from his world to make the two boys an offer they can't - but must -refuse.